Targeting immune‐driven opioid analgesia by sigma‐1 receptors: Opening the door to novel perspectives for the analgesic use of sigma‐1 antagonists
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2018.02.008
Abstract: Graphical abstract Figure. No caption available. ABSTRACT Immune cells have a known role in pronociception, since they release a myriad of inflammatory algogens which interact with neurons to facilitate pain signaling. However, these cells also… read more here.
Keywords: targeting immune; sigma; sigma antagonists; opioid analgesia ... See more keywords
Editorial: Targeting the Immune System to Treat Hepatitis B Virus Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.868616
Abstract: 1 Institute of Biomedical Research, Hubei Clinical Research Center for Precise Diagnosis and Therapy of Liver Cancer, Taihe Hospital, Hubei University of Medicine, Shiyan, China, 2 Department of Infectious Diseases, Union Hospital, Tongji Medical College,… read more here.
Keywords: editorial targeting; immune system; targeting immune; infection ... See more keywords
Targeting immune-onco-metabolism for precision cancer therapy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1124715
Abstract: Immune cells play a key role in host defence against infection and cancer. Unlike infection, cancer is a multidimensional disease where cancer cells require continuous activation of certain pathways to sustain their growth and survival.… read more here.
Keywords: oncology; metabolism; targeting immune; immune onco ... See more keywords
Targeting Immune Senescence in Atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113059
Abstract: Atherosclerosis is one of the main underlying causes of cardiovascular diseases (CVD). It is associated with chronic inflammation and intimal thickening as well as the involvement of multiple cell types including immune cells. The engagement… read more here.
Keywords: senescence atherosclerosis; targeting immune; senescence; atherosclerosis ... See more keywords
Tyk2 Targeting in Immune-Mediated Inflammatory Diseases
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043391
Abstract: The Janus kinase (Jak)/signal transducer and activating protein (STAT) pathways mediate the intracellular signaling of cytokines in a wide spectrum of cellular processes. They participate in physiologic and inflammatory cascades and have become a major… read more here.
Keywords: tyk2 targeting; targeting immune; immune mediated; mediated inflammatory ... See more keywords
mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15081017
Abstract: mRNA delivery has recently gained substantial interest for possible use in vaccines. Recently approved mRNA vaccines are administered intramuscularly where they transfect antigen-presenting cells (APCs) near the site of administration, resulting in an immune response.… read more here.
Keywords: cells spleen; targeting immune; mrna loaded; immune cells ... See more keywords