Targeting intrinsically disordered proteins involved in cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03347-3
Abstract: Intrinsically disordered proteins (IDPs) do not have a well-defined structure under physiological conditions, but they have key roles in cell signaling and regulation, and they are frequently related to the development of diseases, such as… read more here.
Keywords: involved cancer; targeting intrinsically; cancer; targeting idps ... See more keywords
Targeting intrinsically disordered regions facilitates discovery of calcium channels 3.2 inhibitory peptides for adeno-associated virus–mediated peripheral analgesia
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DOI: 10.1097/j.pain.0000000000002650
Abstract: Supplemental Digital Content is Available in the Text. Targeting intrinsically disordered regions facilitates discovery of T-type/calcium channels 3.2 (CaV3.2) inhibitory peptides. Adeno-associated virus–mediated expression of prototypic CaV3.2iPA1 and 2 in dorsal root ganglia primary sensory… read more here.
Keywords: calcium; intrinsically disordered; facilitates discovery; regions facilitates ... See more keywords