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Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00336
Abstract: The successful development of targeted nanoparticle (NP)-based therapeutics depends on the effective conjugation of targeting ligands to the NP. However, conventional methods based on chemical reactive groups such as N-hydroxysuccinimide, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide, and maleimide have…
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Keywords:
system;
targeting ligand;
spytag spycatcher;
her2 ... See more keywords
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Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.7b00013
Abstract: Safety and efficacy constitute the major criteria governing regulatory approval of any new drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic agent with a targeting ligand that exhibits…
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Keywords:
ligand targeted;
drug delivery;
targeting ligand;
drug ... See more keywords