Targeting lysosomes in human disease: from basic research to clinical applications
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00778-y
Abstract: In recent years, accumulating evidence has elucidated the role of lysosomes in dynamically regulating cellular and organismal homeostasis. Lysosomal changes and dysfunction have been correlated with the development of numerous diseases. In this review, we… read more here.
Keywords: targeting lysosomal; research clinical; lysosomes human; targeting lysosomes ... See more keywords
Advances in Drug Discovery Targeting Lysosomal Membrane Proteins
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040601
Abstract: Lysosomes are essential organelles of eukaryotic cells and are responsible for various cellular functions, including endocytic degradation, extracellular secretion, and signal transduction. There are dozens of proteins localized to the lysosomal membrane that control the… read more here.
Keywords: targeting lysosomal; advances drug; membrane proteins; lysosomal membrane ... See more keywords