Targeting the lysosome: Mechanisms and treatments for nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30274
Abstract: The multiple functions of the lysosome, including degradation, nutrient sensing, signaling, and gene regulation, enable the lysosome to regulate lipid metabolism at different levels. In this review, I summarize the recent studies on lysosomal regulation… read more here.
Keywords: nonalcoholic fatty; lysosome mechanisms; targeting lysosome; fatty liver ... See more keywords
Targeting lysosome function causes selective cytotoxicity in VHL-inactivated renal cell carcinomas.
Sign Up to like & getrecommendations! Published in 2019 at "Carcinogenesis"
DOI: 10.1093/carcin/bgz161
Abstract: The inactivation of the tumor suppressor gene, von Hippel-Lindau (VHL), has been identified as the earliest event in renal cell carcinoma (RCC) development. The loss of heterogeneity by chromosome 3p deletion followed by inactivating mutations… read more here.
Keywords: renal cell; vhl; lysosome function; targeting lysosome ... See more keywords