Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.030
Abstract: Aberrant macrophage activation during intracellular infection generates immunopathologies that can cause severe human morbidity. A better understanding of immune subversion strategies and macrophage phenotypic and functional responses is necessary to design host-directed intervention strategies. Here,… read more here.
Keywords: response; macrophage; strategy; targeting macrophage ... See more keywords
Targeting macrophage-mediated tumor cell phagocytosis: An overview of phagocytosis checkpoints blockade, nanomedicine intervention, and engineered CAR-macrophage therapy.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108499
Abstract: Immunotherapy has been developing at an unprecedented speed with promising therapeutic outcomes in the wide spectrum of cancers. Up until now, most immunotherapies have focused on adaptive immunity; however, investigating the potential of macrophage phagocytosis… read more here.
Keywords: targeting macrophage; phagocytosis checkpoints; macrophage; car macrophage ... See more keywords
Targeting the Macrophage: Immune Cells May Be the Key to Phthalate-Induced Liver Toxicity
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Health Perspectives"
DOI: 10.1289/ehp11026
Abstract: Scanning electron micrograph of hepatocytes, a macrophage, and red blood cells read more here.
Keywords: macrophage; macrophage immune; targeting macrophage; cells may ... See more keywords