Cre Driver Mice Targeting Macrophages.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7837-3_24
Abstract: The Cre/loxP system is a widely applied technology for site-specific genetic manipulation in mice. This system allows for deletion of the genes of interest in specific cells, tissues, and whole organism to generate a diversity… read more here.
Keywords: targeting macrophages; biology; driver mice; mice ... See more keywords
The Promise of Targeting Macrophages in Cancer Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-16-3122
Abstract: Cancer therapy has developed around the concept of killing, or stopping the growth of, the cancer cells. Molecularly targeted therapy is the modern expression of this paradigm. Increasingly, however, the realization that the cancer has… read more here.
Keywords: therapy; targeting macrophages; promise targeting; macrophages cancer ... See more keywords
Targeting Macrophages in Cancer: From Bench to Bedside
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2018.00049
Abstract: Macrophages are a major component of the tumor microenvironment and orchestrate various aspects of immunity. Within tumors, macrophages can reversibly alter their endotype in response to environmental cues, including hypoxia and stimuli derived from other… read more here.
Keywords: cancer bench; targeting macrophages; bench bedside; macrophages cancer ... See more keywords
Targeting Macrophages as a Therapeutic Option in Coronavirus Disease 2019
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.577571
Abstract: Immune cells of the monocyte/macrophage lineage are characterized by their diversity, plasticity, and variety of functions. Among them, macrophages play a central role in antiviral responses, tissue repair, and fibrosis. Macrophages can be reprogrammed by… read more here.
Keywords: disease 2019; coronavirus disease; targeting macrophages; macrophage ... See more keywords
Targeting Macrophages as a Potential Therapeutic Intervention: Impact on Inflammatory Diseases and Cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19071953
Abstract: Macrophages, cells belonging to the innate immune system, present a high plasticity grade, being able to change their phenotype in response to environmental stimuli. They play central roles during development, homeostatic tissue processes, tissue repair,… read more here.
Keywords: targeting macrophages; diseases cancer; macrophages potential; inflammatory diseases ... See more keywords
Liposomes; from synthesis to targeting macrophages
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical Research"
DOI: 10.35841/biomedicalresearch.30-19-058
Abstract: Liposomes are a proposed tool to use for cell and tissue specific drug targeting. Because of their phospholipid membranes and carrying capacity within their spheres, liposomes are of particular interest for clinical applications. Stealth liposomes… read more here.
Keywords: targeting macrophages; synthesis targeting; liposomes synthesis; passive loading ... See more keywords