Targeting Mast Cell Activation and MIF-Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202509930
Abstract: Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) is increasingly applied in pancreatic ductal adenocarcinoma (PDAC), yet its effects on the tumor microenvironment (TME) remain incompletely defined. By integrating eight single‐cell RNA sequencing datasets and nine multicenter transcriptomic… read more here.
Keywords: targeting mast; mif; cancer; mast cell ... See more keywords