Articles with "targeting mcl" as a keyword



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Knockdown of microRNA‐203 alleviates LPS‐induced injury by targeting MCL‐1 in C28/I2 chondrocytes

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Published in 2017 at "Experimental Cell Research"

DOI: 10.1016/j.yexcr.2017.07.034

Abstract: &NA; Several microRNAs (miRs) are associated with osteoarthritis (OA) and are also functionally implicated in the pathogenesis of the disease. This study was aimed to investigate the potential roles of miR‐203 in the development and… read more here.

Keywords: targeting mcl; cell; lps induced; mir 203 ... See more keywords
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Abstract B068: Treatment combinations targeting MCL-1 and BCL-xL exert synergistic anti-tumor effects in AR-V7 expressing CRPC cell lines

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.prca2023-b068

Abstract: Therapeutic agents that overcome acquired resistance to current androgen receptor (AR) pathway targeted therapies in patients with castration-resistant prostate cancer (CRPC) remain an unmet clinical need. A multitude of pathways are implicated in acquired treatment… read more here.

Keywords: mcl bcl; crpc; treatment; mcl ... See more keywords