Targeting metabolic driving and minimization of by-products synthesis for high-yield production of D-pantothenate in Escherichia coli.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology journal"
DOI: 10.1002/biot.202100431
Abstract: BACKGROUND D-Pantothenate (DPA) is an important functional chemical that has been widely applied in healthcare, cosmetics, animal food and feed industries. METHODS AND RESULTS In this study, a high-yield DPA-producing strain was constructed by metabolic… read more here.
Keywords: production; high yield; minimization; metabolic driving ... See more keywords
Targeting Metabolic Plasticity and Flexibility Dynamics for Cancer Therapy.
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DOI: 10.1158/2159-8290.cd-20-0844
Abstract: Cancer cells continuously rewire their metabolism to fulfill their need for rapid growth and survival while subject to changes in environmental cues. Thus, a vital component of a cancer cell lies in its metabolic adaptability.… read more here.
Keywords: therapy; plasticity flexibility; cancer; cancer therapy ... See more keywords
Targeting the Metabolic Rewiring in Pancreatic Cancer and Its Tumor Microenvironment
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DOI: 10.3390/cancers14184351
Abstract: Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is characterized by its unique metabolic properties that are established both in a cell-intrinsic and -extrinsic manner, dictated by oncogenic KRAS signaling and shaped in close interaction with the… read more here.
Keywords: targeting metabolic; microenvironment; metabolic rewiring; tumor microenvironment ... See more keywords