Articles with "targeting mir" as a keyword



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CircRNA RNF10 inhibits tumorigenicity by targeting miR‐942‐5p/GOLIM4 axis in breast cancer

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Published in 2022 at "Environmental and Molecular Mutagenesis"

DOI: 10.1002/em.22506

Abstract: We aimed to explore the action of a circRNA produced by ring finger protein 10 (circ_RNF10; hsa_circ_0028899) in the malignant behaviors of breast cancer (BC) and to explore its potential action‐of‐mechanism. The levels of circ_RNF10,… read more here.

Keywords: golim4; circ rnf10; breast cancer; targeting mir ... See more keywords
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Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis.

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Published in 2019 at "Cancer letters"

DOI: 10.1016/j.canlet.2019.02.014

Abstract: Evasion of apoptosis is a major contributing factor to the development of chemo- and radiotherapy resistance. Therefore, activation of non-apoptotic programmed cell death (PCD) could be an effective alternative against apoptosis-resistant cancers. In this study,… read more here.

Keywords: pyroptosis; targeting mir; pelp1; metformin induces ... See more keywords
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CircRNA circ_0043533 facilitates cell growth in polycystic ovary syndrome by targeting miR-1179.

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Published in 2022 at "Reproductive biology"

DOI: 10.1016/j.repbio.2022.100637

Abstract: Increasing evidence indicates that circular RNAs (CircRNAs) have an important role in human diseases, including polycystic ovary syndrome (PCOS). Recently, circ_0043533, a novel circRNA, was proposed to be involved in the progression of PCOS. However,… read more here.

Keywords: targeting mir; polycystic ovary; ovary syndrome; circ 0043533 ... See more keywords
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Circ_0075804 Regulates the Expression of LASP1 by Targeting miR-1287-5p and Thus Affects the Biological Process of Retinoblastoma

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Published in 2022 at "Current Eye Research"

DOI: 10.1080/02713683.2022.2053164

Abstract: Abstract Purpose Increasing evidence reveals that circular RNA (circRNA) dysregulation is involved in retinoblastoma (RB) pathogenesis. To further realize the development of RB, we investigated the role and regulatory mechanism of circ_0075804 in RB. Methods… read more here.

Keywords: mir 1287; targeting mir; circ 0075804; expression ... See more keywords
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Silencing of circ‐NT5C2 retards the progression of IL‐1β–induced osteoarthritis in an in vitro cell model by targeting the miR‐142‐5p/NAMPT axis

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Published in 2022 at "Microbiology and Immunology"

DOI: 10.1111/1348-0421.13046

Abstract: Osteoarthritis (OA) is a degenerative disease that occurs mostly in the elderly, and its specific pathogenesis is still unknown, but recent studies have found that circular RNA generally display aberrant expression in OA. Our study… read more here.

Keywords: cell model; circ nt5c2; targeting mir; mir 142 ... See more keywords
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HCG11 up-regulation induced by ELK4 suppressed proliferation in vestibular schwannoma by targeting miR-620/ELK4

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Published in 2021 at "Cancer Cell International"

DOI: 10.1186/s12935-020-01691-0

Abstract: Background Vestibular schwannoma (VS) is a kind of benign tumor deriving from the acoustic nerve sheath. Substantial long non-coding RNAs (lncRNAs) were illustrated to have crucial roles in multiple cancers. However, few lncRNAs were elucidated… read more here.

Keywords: mir 620; vestibular schwannoma; targeting mir; hcg11 ... See more keywords

RUNX3 regulates hepatocellular carcinoma cell metastasis via targeting miR-186/E-cadherin/EMT pathway.

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.18424

Abstract: Runt-related transcription factor 3 (RUNX3) has been reported as a tumor suppressor in some kinds of cancers. In the present study, hepatocellular carcinoma (HCC) microarray analysis showed that RUNX3 expression was significantly lower in HCC… read more here.

Keywords: hepatocellular carcinoma; targeting mir; metastasis; runx3 ... See more keywords
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LncRNA NORAD mediates KMT2D expression by targeting miR-204-5p and affects the growth of gastric cancer

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Published in 2022 at "Journal of Gastrointestinal Oncology"

DOI: 10.21037/jgo-22-1014

Abstract: Background Long non-coding ribonucleic acids (lncRNAs) are a class of non-coding RNAs implicated in the development of many malignancies, including gastric cancer (GC). In this study, we investigated the functions and molecular mechanisms of non-coding… read more here.

Keywords: expression targeting; expression; targeting mir; mir 204 ... See more keywords
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Osteoblasts-Derived Exosomal lncRNA-MALAT1 Promotes Osteoclastogenesis by Targeting the miR-124/NFATc1 Signaling Axis in Bone Marrow-Derived Macrophages

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Published in 2023 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s395607

Abstract: Objective Emerging studies have explained the crucial role of non-coding RNA (lncRNA) in various pathological progressions. The study was designed to examine the role of lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and miRNA-124 in… read more here.

Keywords: lncrna malat1; 124 nfatc1; mir 124; targeting mir ... See more keywords
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CircFAM120B Blocks the Development of Colorectal Cancer by Activating TGF-Beta Receptor II Expression via Targeting miR-645

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.682543

Abstract: Circular RNAs (circRNAs) are implicated in various human cancers, including colorectal cancer (CRC). The objective of this study was to investigate the function and regulatory mechanism of a novel circRNA, circFAM120B, in CRC development. The… read more here.

Keywords: mir 645; tgfbr2; glycolysis; targeting mir ... See more keywords

Knockdown of lncRNA SNHG4 suppresses gastric cancer cell proliferation and metastasis by targeting miR-204-5p.

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Published in 2021 at "Neoplasma"

DOI: 10.4149/neo_2021_200914n981

Abstract: Long non-coding RNAs (lncRNAs) have been identified as critical regulators in gastric cancer (GC) progression. However, whether lncRNA small nucleolar host gene 4 (SNHG4) functions in GC development remains unknown. In this study, the bio-functional… read more here.

Keywords: mir 204; snhg4; gastric cancer; proliferation ... See more keywords