Targeting mRNA translation in Parkinson's disease.
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DOI: 10.1016/j.drudis.2019.04.003
Abstract: Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The exact cause(s) of PD is not well understood, although genetic mutations are associated with some forms of the disease. Many of these mutations,… read more here.
Keywords: targeting mrna; mrna translation; translation; parkinson disease ... See more keywords
Abstract 280: Targeting mRNA pseudouridylation to suppress neuroblastoma metabolism
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DOI: 10.1158/1538-7445.am2023-280
Abstract: Pseudouridylation of mRNA is a common epigenetic modification that reduces RNA conformational flexibility and increases its structural stability and may increase its availability for translation. RNA pseudouridylation is catalyzed by the family of pseudouridine synthases,… read more here.
Keywords: metabolism; mrna pseudouridylation; pseudouridylation; targeting mrna ... See more keywords