A PI polyamide–TPP conjugate targeting a mtDNA mutation induces cell death of cancer cells with the mutation
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DOI: 10.1111/cas.14912
Abstract: Mitochondrial DNA (mtDNA) mutations occur frequently in cancer cells, and some of them are often homoplasmic. Targeting such mtDNA mutations could be a new method for killing cancer cells with minimal impact on normal cells.… read more here.
Keywords: dna; mtdna mutation; cancer cells; cancer ... See more keywords