Genetic characterization and therapeutic targeting of MYC‐rearranged T cell acute lymphoblastic leukaemia
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DOI: 10.1111/bjh.15425
Abstract: Author(s): Milani, Gloria; Matthijssens, Filip; Van Loocke, Wouter; Durinck, Kaat; Roels, Juliette; Peirs, Sofie; Thenoz, Morgan; Pieters, Tim; Reunes, Lindy; Lintermans, Beatrice; Vandamme, Niels; Lammens, Tim; Van Roy, Nadine; Van Nieuwerburgh, Filip; Deforce, Dieter; Schwab,… read more here.
Keywords: myc rearranged; characterization therapeutic; therapeutic targeting; van ... See more keywords
Abstract 523: Targeting myc-amplified cancers with a novel prodrug inhibiting aurora A kinase
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DOI: 10.1158/1538-7445.am2023-523
Abstract: Upregulation of Aurora kinases has been associated with increased tumor progression, and thus they are appealing targets for the development of anti-cancer therapies. In addition to have a critical role in cell cycle regulation, Aurora… read more here.
Keywords: aurora kinase; myc amplified; kinase; targeting myc ... See more keywords
Targeting Myc Interacting Proteins as a Winding Path in Cancer Therapy
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DOI: 10.3389/fphar.2021.748852
Abstract: MYC, as a well-known oncogene, plays essential roles in promoting tumor occurrence, development, invasion and metastasis in many kinds of solid tumors and hematologic neoplasms. In tumors, the low expression and the short half-life of… read more here.
Keywords: targeting myc; proteins winding; interacting proteins; cancer ... See more keywords
Corrigendum: Targeting Myc Interacting Proteins as a Winding Path in Cancer Therapy
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DOI: 10.3389/fphar.2021.785732
Abstract: [This corrects the article DOI: 10.3389/fphar.2021.748852.]. read more here.
Keywords: proteins winding; interacting proteins; winding path; corrigendum targeting ... See more keywords
Improved antitumor activity against prostate cancer via synergistic targeting of Myc and GFAT-1
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DOI: 10.7150/thno.76614
Abstract: Inhibition of Myc promotes the regression of many types of tumors, including prostate cancer. However, the success of anti-Myc therapy is hampered by the lack of a strategy to effectively deliver the inhibitors to the… read more here.
Keywords: targeting myc; myc gfat; prostate cancer; cancer ... See more keywords