Targeting myeloid cells in the tumor sustaining microenvironment.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.10.013
Abstract: Myeloid cells are the most abundant cells in the tumor microenvironment (TME). The tumor recruits and modulates endogenous myeloid cells to tumor-associated macrophages (TAM), dendritic cells (DC), myeloid-derived suppressor cells (MDSC) and neutrophils (TAN), to… read more here.
Keywords: targeting myeloid; myeloid cells; tumor sustaining; cancer ... See more keywords
Abstract 70: Targeting Myeloid Specific Neutrophil Integrin α9β1 Improves Stroke Outcome Following Transient Cerebral Ischemia in Comorbid Condition of Hyperlipidemia
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/str.49.suppl_1.70
Abstract: Background and Hypothesis: Neutrophils infiltration following reperfusion is the hallmark of ischemic stroke. Integrin α9β1 is highly expressed on neutrophils, upregulated upon activation, stabiliz... read more here.
Keywords: targeting myeloid; integrin; specific neutrophil; neutrophil integrin ... See more keywords
Editorial: Targeting Myeloid Cells to Fight Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02835
Abstract: Refractory and relapsed cancer patients often develop resistance mechanisms associated with an immunosuppressive tumor microenvironment (TME). Indeed, the TME is critically involved not only in tumor growth, invasion and dissemination, but in immune editing and… read more here.
Keywords: fight cancer; targeting myeloid; myeloid cells; editorial targeting ... See more keywords
Evolution and Targeting of Myeloid Suppressor Cells in Cancer: A Translational Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030510
Abstract: Simple Summary Immunotherapy is achieving impressive results in the treatment of several cancers. While the main strategies aim to re-invigorate the specific lymphocyte anti-tumor response, many studies underline that altered myeloid cell frequency and functions… read more here.
Keywords: suppressor cells; myeloid; targeting myeloid; evolution targeting ... See more keywords