Unraveling and Targeting Myocardial Regeneration Deficit in Diabetes
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DOI: 10.3390/antiox11020208
Abstract: Cardiomyopathy is a common complication in diabetic patients. Ventricular dysfunction without coronary atherosclerosis and hypertension is driven by hyperglycemia, hyperinsulinemia and impaired insulin signaling. Cardiomyocyte death, hypertrophy, fibrosis, and cell signaling defects underlie cardiomyopathy. Notably,… read more here.
Keywords: unraveling targeting; regeneration deficit; targeting myocardial; myocardial regeneration ... See more keywords
Targeting Myocardial Fibrosis—A Magic Pill in Cardiovascular Medicine?
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DOI: 10.3390/pharmaceutics14081599
Abstract: Fibrosis, characterized by an excessive accumulation of extracellular matrix, has long been seen as an adaptive process that contributes to tissue healing and regeneration. More recently, however, cardiac fibrosis has been shown to be a… read more here.
Keywords: myocardial fibrosis; fibrosis magic; magic pill; targeting myocardial ... See more keywords