T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
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DOI: 10.1038/s41467-017-01830-8
Abstract: Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because attempts to target tumors directly have yielded limited benefit, we instead target endogenous… read more here.
Keywords: delivery immunotherapy; delivery; targeting nanoparticles; cell ... See more keywords
Dual targeting nanoparticles for epilepsy therapy
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DOI: 10.1039/d2sc03298h
Abstract: For epilepsy therapy, one-third of the patients worldwide are resistant to antiepileptic drugs mainly due to the existence of the blood–brain barrier (BBB) that prevents the drugs from reaching the epileptic lesions. Here, we design… read more here.
Keywords: bbb; dual targeting; epilepsy therapy; nanoparticles epilepsy ... See more keywords
Tumor necrosis factor-α small interfering RNA alveolar epithelial cell-targeting nanoparticles reduce lung injury in C57BL/6J mice with sepsis
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DOI: 10.1177/0300060520984652
Abstract: Background The role of tumor necrosis factor (TNF)-α small interfering (si)RNA alveolar epithelial cell (AEC)-targeting nanoparticles in lung injury is unclear. Methods Sixty C57BL/6J mice with sepsis were divided into normal, control, sham, 25 mg/kg,… read more here.
Keywords: sepsis; cell; tumor necrosis; targeting nanoparticles ... See more keywords
Novel Tumor-Targeting Nanoparticles for Cancer Treatment—A Review
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DOI: 10.3390/ijms23095253
Abstract: Being one of the leading causes of death and disability worldwide, cancer represents an ongoing interdisciplinary challenge for the scientific community. As currently used treatments may face limitations in terms of both efficiency and adverse… read more here.
Keywords: cancer; nanoparticles cancer; tumor targeting; targeting nanoparticles ... See more keywords