Articles with "targeting nrs" as a keyword



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Allosteric small molecule modulators of nuclear receptors

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Published in 2019 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2019.01.022

Abstract: Nuclear Receptors (NRs) are multi-domain proteins, whose natural regulation occurs via ligands for a classical, orthosteric, binding pocket and via intra- and inter-domain allosteric mechanisms. Allosteric modulation of NRs via synthetic small molecules has recently… read more here.

Keywords: nuclear receptors; small molecule; small molecules; molecule modulators ... See more keywords