The Potential of Targeting P53 and HSP90 Overcoming Acquired MAPKi-Resistant Melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-019-0622-9
Abstract: Opinion StatementMelanoma is the deadliest form of skin cancer worldwide. The rising melanoma incidence and mortality, along with its high propensity for metastasis highlights the urgency to identify more effective therapeutic targets. Approximately, one half… read more here.
Keywords: melanoma; targeting p53; acquired mapki; p53 hsp90 ... See more keywords
Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13184681
Abstract: Simple Summary The p53 pathway plays a fundamental role in preventing the accumulation of unrepaired DNA damage. Unsurprisingly, cancer cells often break this protective barrier by inactivating either p53 itself or other proteins along this… read more here.
Keywords: cll; targeting p53; cancer; p53 ... See more keywords