Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening
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DOI: 10.3389/fphar.2022.1026306
Abstract: Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective DNA repair. The anti-tumor activities… read more here.
Keywords: anti tumor; novel anti; targeting parp; tumor compounds ... See more keywords