Targeting Peptide-Based Probes for Molecular Imaging and Diagnosis.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201804827
Abstract: A series of novel peptide-based molecular probes for different biomarkers is highlighted herein. These probes can provide targeted recognition with high affinity, high specificity, high penetration, and rapid excretion ability. These sensitive peptides can achieve… read more here.
Keywords: targeting peptide; diagnosis; probes molecular; peptide based ... See more keywords
Targeting peptide‐mediated interactions in omics
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200175
Abstract: Peptide‐mediated interactions (PMIs) play a crucial role in cell signaling network, which are responsible for about half of cellular protein–protein associations in the human interactome and have recently been recognized as a new kind of… read more here.
Keywords: peptide mediated; mediated interactions; interactions omics; targeting peptide ... See more keywords
Repurposing a drug targeting peptide for targeting antimicrobial peptides against Staphylococcus
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Letters"
DOI: 10.1007/s10529-019-02779-y
Abstract: ObjectivesTargeted therapies seek to selectively eliminate a pathogen without disrupting the resident microbial community. However, with selectivity comes the potential for developing bacterial resistance. Thus, a diverse range of targeting peptides must be made available.ResultsTwo… read more here.
Keywords: targeting peptide; repurposing drug; antimicrobial peptides; targeting antimicrobial ... See more keywords
Traceable PEO-poly(ester) micelles for breast cancer targeting: The effect of core structure and targeting peptide on micellar tumor accumulation.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.08.001
Abstract: Traceable poly(ethylene oxide)-poly(ester) micelles were developed through chemical conjugation of a near-infrared (NIR) dye to the poly(ester) end by click chemistry. This strategy was tried for micelles with poly(ε-caprolactone) (PCL) or poly(α-benzyl carboxylate-ε-caprolactone) (PBCL) cores.… read more here.
Keywords: targeting peptide; cancer targeting; breast cancer; poly ester ... See more keywords
Enhanced protection against hypoxia/reoxygenation-induced apoptosis in H9c2 cells by puerarin-loaded liposomes modified with matrix metalloproteinases-targeting peptide and triphenylphosphonium.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of liposome research"
DOI: 10.1080/08982104.2023.2193845
Abstract: Based on the inhibition of mitochondrial permeability transition pore (mPTP) opening, puerarin (PUE) has a good potential to reduce myocardial ischemia/reperfusion injury (MI/RI). However, the lack of targeting of free PUE makes it difficult to… read more here.
Keywords: hypoxia reoxygenation; h9c2 cells; triphenylphosphonium; pue ... See more keywords
Abstract 3180: Targeting peptide-loaded-DC CIK cells induce a specific antitumor response
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-3180
Abstract: Currently, immunotherapy has become an effective alternative therapeutic approach for cancers. Cytokine-induced killer (CIK) cells have a higher proliferation rate, increased efficacy with few side-effects, and non- MHC-restricted killing after co-culturing with dendritic cells (DCs).… read more here.
Keywords: loaded cik; peptide loaded; antitumor; cik cells ... See more keywords
Tumor-targeting delivery of herb-based drugs with cell-penetrating/tumor-targeting peptide-modified nanocarriers
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s156616
Abstract: Cancer has become one of the leading causes of mortality globally. The major challenges of conventional cancer therapy are the failure of most chemotherapeutic agents to accumulate selectively in tumor cells and their severe systemic… read more here.
Keywords: targeting peptide; modified nanocarriers; delivery; cell penetrating ... See more keywords
The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2018.00048
Abstract: The ribosome is one of the major targets in the cell for clinically used antibiotics. However, the increase in multidrug resistant bacteria is rapidly reducing the effectiveness of our current arsenal of ribosome-targeting antibiotics, highlighting… read more here.
Keywords: mechanisms action; ribosome targeting; targeting peptide; peptide antibiotics ... See more keywords