Insights into the Targeting Potential of Thymoquinone for Therapeutic Intervention Against Triple-negative Breast Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug targets"
DOI: 10.2174/1389450118666170612095959
Abstract: BACKGROUND Thymoquinone (TQ) is a bioactive phytoconstituent obtained from Nigella sativa (black seeds). It has promising potential in cancer prevention. OBJECTIVE Previous studies have shown that TQ can modulate signaling pathways responsible for cancer progression,… read more here.
Keywords: negative breast; targeting potential; breast cancer; cancer ... See more keywords
Targeting IL-6 Is a Potential Treatment for Primary Cystic Craniopharyngioma
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00791
Abstract: Adamantinomatous craniopharyngioma (ACP) makes up between 6 and 8% of pediatric brain tumors and is the most common pediatric tumor arising in the sellar/suprasellar region of the brain. The 10-year survival for patients diagnosed with… read more here.
Keywords: potential treatment; targeting potential; craniopharyngioma; treatment primary ... See more keywords
In Vivo Preclinical Assessment of the VEGF Targeting Potential of the Newly Synthesized [52Mn]Mn-DOTAGA-Bevacizumab Using Experimental Cervix Carcinoma Mouse Model
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13020236
Abstract: Among humanized monoclonal antibodies, bevacizumab specifically binds to vascular endothelial growth factor A (VEGF-A). VEGF-A is an overexpressed biomarker in cervix carcinoma and is involved in the development and maintenance of tumor-associated neo-angiogenesis. The non-invasive… read more here.
Keywords: cervix; dotaga bevacizumab; cervix carcinoma; targeting potential ... See more keywords
Transcription Factors with Targeting Potential in Gliomas
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073720
Abstract: Gliomas portray a large and heterogeneous group of CNS tumors, encompassing a wide range of low- to high-grade tumors, as defined by histological and molecular characteristics. The identification of signature mutations and other molecular abnormalities… read more here.
Keywords: targeting potential; gliomas; factors targeting; transcription factors ... See more keywords