Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours
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DOI: 10.1038/onc.2017.93
Abstract: KRAS is one of the most frequently mutated oncogenes in human non-small cell lung cancers (NSCLCs). RAS proteins trigger multiple effector signalling pathways including the highly conserved RAF-MAPK pathway. CRAF, a direct RAS effector protein,… read more here.
Keywords: craf; targeting prohibitins; chemical ligands; prohibitins chemical ... See more keywords