Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling
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DOI: 10.1002/advs.202506131
Abstract: Neuroblastoma (NB), a pediatric solid malignancy, is distinguished by hetergenous clinical characteristics, including tumor aggressiveness or spontaneous regression. Nevertheless, the regulatory mechanisms and therapeutic approaches underlying these processes are still mainly unknown. Herein, RAR‐related orphan… read more here.
Keywords: biogenesis; targeting rbm10; liquid condensates; lysosomal biogenesis ... See more keywords