Targeting regulatory T cells in anti‐PD‐1/PD‐L1 cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2021 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13129
Abstract: The programmed death (PD)‐1/PD‐ligand (PD‐L) pathway and regulatory T cells (Tregs) are essential for the maintenance of immune tolerance. Their activation in the tumour microenvironment contributes to the evasion of the transformed cells from the… read more here.
Keywords: cells anti; targeting regulatory; regulatory cells; cancer immunotherapy ... See more keywords
Targeting regulatory T cells for cardiovascular diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1126761
Abstract: Cardiovascular diseases (CVDs) are the leading cause of death and disability worldwide. The CVDs are accompanied by inflammatory progression, resulting in innate and adaptive immune responses. Regulatory T cells (Tregs) have an immunosuppressive function and… read more here.
Keywords: regulatory cells; cells cardiovascular; targeting regulatory; cvds ... See more keywords
Targeting Regulatory T Cells for Therapy of Lupus Nephritis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.806612
Abstract: Lupus glomerulonephritis (LN) is a complex autoimmune disease characterized by circulating autoantibodies, immune-complex deposition, immune dysregulation and defects in regulatory T cell (Tregs). Treatment options rely on general immunosuppressants and steroids that have serious side… read more here.
Keywords: cells therapy; regulatory cells; targeting regulatory; lupus nephritis ... See more keywords