Expanding the targeting scope of FokI‐dCas nuclease systems with SpRY and Mb2Cas12a
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DOI: 10.1002/biot.202100571
Abstract: CRISPR‐Cas9 and Cas12a are widely used sequence‐specific nucleases (SSNs) for genome editing. The nuclease domains of Cas proteins can induce DNA double strand breaks upon RNA guided DNA targeting. Zinc finger nucleases (ZFNs) and Transcription… read more here.
Keywords: system; dna; foki; targeting scope ... See more keywords