Articles with "targeting secretase" as a keyword



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Small molecules targeting γ-secretase and their potential biological applications.

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Published in 2022 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2022.114169

Abstract: The γ-secretase is a large transmembrane protein complex composed of four distinct units. It has aroused numerous attention over the past two decades as its intriguing role in mediating intramembrane proteolysis. γ-Secretase controls the cleavage… read more here.

Keywords: molecules targeting; potential biological; small molecules; secretase ... See more keywords