Articles with "targeting serotonin" as a keyword



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Development of selective agents targeting serotonin 5HT1A receptors with subnanomolar activities based on a coumarin core.

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Published in 2017 at "MedChemComm"

DOI: 10.1039/c7md00281e

Abstract: A series of 18 new 5-[3-(4-aryl-1-piperazinyl)propoxy]coumarin derivatives from the corresponding bromoalkyl derivatives have been designed and synthesized by us using a microwave-assisted protocol. Radioligand binding assays of this series of compounds as well as a… read more here.

Keywords: targeting serotonin; development selective; 5ht1a receptors; serotonin 5ht1a ... See more keywords