Articles with "targeting siglec" as a keyword



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A sulfonamide sialoside analog for targeting Siglec-8 and -F on im-mune cells.

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Published in 2019 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.9b05769

Abstract: The Siglec family of sialic acid binding im-munoglobulin-like cell surface receptors have emerged as attractive targets for cell directed therapies due to their restricted expression on immune cells, endocytic properties and ability to modulate receptor… read more here.

Keywords: siglec; sialoside analog; sulfonamide sialoside; targeting siglec ... See more keywords