Targeting the signaling in Epstein–Barr virus-associated diseases: mechanism, regulation, and clinical study
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00376-4
Abstract: Epstein–Barr virus-associated diseases are important global health concerns. As a group I carcinogen, EBV accounts for 1.5% of human malignances, including both epithelial- and lymphatic-originated tumors. Moreover, EBV plays an etiological and pathogenic role in… read more here.
Keywords: epstein barr; barr virus; associated diseases; virus associated ... See more keywords
The protective activity of natural flavonoids against osteoarthritis by targeting NF-κB signaling pathway
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1117489
Abstract: Osteoarthritis (OA) is a typical joint disease associated with chronic inflammation. The nuclear factor-kappaB (NF-κB) pathway plays an important role in inflammatory activity and inhibiting NF-κB-mediated inflammation can be a potential strategy for treating OA.… read more here.
Keywords: targeting signaling; natural flavonoids; signaling pathway; protective activity ... See more keywords
Targeting Signaling Pathway Networks in Several Malignant Tumors: Progresses and Challenges
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.675675
Abstract: Malignant tumors remain the health problem of highest concern among people worldwide due to its high mortality and recurrence. Lung, gastric, liver, colon, and breast cancers are among the top five malignant tumors in terms… read more here.
Keywords: signaling pathways; pathway networks; signaling pathway; malignant tumors ... See more keywords
Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review
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DOI: 10.3390/biomedicines10020261
Abstract: Among the cell populations existing within a tumor, cancer stem cells are responsible for metastasis formation and chemotherapeutic resistance. In the present review, we focus on the transcription factor NF-κB, which is present in every… read more here.
Keywords: targeting signaling; review; cancer stem; stem cells ... See more keywords
Targeting NF-κB Signaling for Multiple Myeloma
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DOI: 10.3390/cancers12082203
Abstract: Multiple myeloma (MM) is the second most common hematologic malignancy in the world. Even though survival rates have significantly risen over the past years, MM remains incurable, and is also far from reaching the point… read more here.
Keywords: multiple myeloma; signaling multiple; targeting signaling; myeloma ... See more keywords