Targeting survivin for therapeutic discovery: past, present, and future promises.
Sign Up to like & getrecommendations! Published in 2017 at "Drug discovery today"
DOI: 10.1016/j.drudis.2017.05.009
Abstract: Survivin, the smallest member of the inhibitor of apoptosis protein (IAP) family, is overexpressed in cells of almost all cancers but not in most normal tissues in adults. Survivin expression is required for cancer cell… read more here.
Keywords: survivin therapeutic; discovery; targeting survivin; drug discovery ... See more keywords
Targeting survivin sensitizes cervical cancer cells to radiation treatment
Sign Up to like & getrecommendations! Published in 2020 at "Bioengineered"
DOI: 10.1080/21655979.2020.1717297
Abstract: ABSTRACT Survivin is an inhibitor of apoptosis protein that functions to inhibit apoptosis, promote proliferation, and enhance invasion. It is selectively up-regulated in many human tumors and implicated in cellular radiation response through its role… read more here.
Keywords: apoptosis; survivin; treatment; targeting survivin ... See more keywords