Amino acid transporters: Emerging roles in drug delivery for tumor-targeting therapy
Sign Up to like & getrecommendations! Published in 2020 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2019.12.002
Abstract: Amino acid transporters, which play a vital role in transporting amino acids for the biosynthesis of mammalian cells, are highly expressed in types of tumors. Increasing studies have shown the feasibility of amino acid transporters… read more here.
Keywords: targeting therapy; acid transporters; tumor targeting; amino acid ... See more keywords
An esterase-activatable curcumin prodrug for tumor-targeting therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03952d
Abstract: A tumor-targeting therapy strategy is urgently needed to increase the accumulation of drugs in tumors and reduce the side effects in normal tissues. Herein, we developed an esterase-activatable curcumin prodrug Cur-RGD for tumor-targeting therapy. Armed… read more here.
Keywords: esterase activatable; activatable curcumin; tumor targeting; targeting therapy ... See more keywords
Phytic acid-modified manganese dioxide nanoparticles oligomer for magnetic resonance imaging and targeting therapy of osteosarcoma
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DOI: 10.1080/10717544.2023.2181743
Abstract: Abstract Osteosarcoma is the most common malignant tumor in the skeletal system with high mortality. Phytic acid (PA) is a natural compound extracted from plant seeds, which shows certain antitumor activity and good bone targeting… read more here.
Keywords: osteosarcoma; spectroscopy; therapy osteosarcoma; targeting therapy ... See more keywords
Lupus nephritis and B-cell targeting therapy
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2017.1366855
Abstract: ABSTRACT Introduction: Lupus Nephritis (LN) is a severe manifestation of Systemic Lupus Erythematosus (SLE) with a significant prognostic impact. Over a prolonged course, an exhaustion of treatment alternatives may occur and further therapeutic options are… read more here.
Keywords: cell targeting; lupus nephritis; nephritis cell; targeting therapy ... See more keywords
Current status and prospects of IL-6–targeting therapy
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2097905
Abstract: ABSTRACT Introduction Persistent and excess IL-6 production often contributes to a variety of immune diseases. IL-6–targeting therapy was first approved for Castleman disease, then rheumatoid arthritis, and now it is broadly used. Furthermore, it has… read more here.
Keywords: disease; therapy; prospects targeting; status prospects ... See more keywords
Therapeutic Approaches Targeting miRNA in Systemic Lupus Erythematosus.
Sign Up to like & getrecommendations! Published in 2022 at "Acta medica Okayama"
DOI: 10.18926/amo/63887
Abstract: Systemic lupus erythematosus (SLE) is a potentially fatal systemic autoimmune disease, and its etiology involves both genetic and environmental factors such as sex hormone imbalance, genetic predisposition, epigenetic regulation, and immunological factors. Dysregulation of microRNA… read more here.
Keywords: lupus erythematosus; targeting therapy; systemic lupus; mirna targeting ... See more keywords
Characterization of molecular pathways for targeting therapy in glioblastoma.
Sign Up to like & getrecommendations! Published in 2020 at "Chinese clinical oncology"
DOI: 10.21037/cco-20-124
Abstract: Glioblastoma remains the most common malignant brain neoplasm in adults. The available therapies for treatment have only modestly extended survival. Traditional chemotherapy agents have shown only slight effectiveness in controlling this disease. The use of… read more here.
Keywords: glioblastoma; pathways targeting; therapy glioblastoma; targeting therapy ... See more keywords