New electrophiles targeting thiols in a reversible covalent manner.
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DOI: 10.1039/d4cc04612a
Abstract: Reversible covalent electrophiles with the advantages of both reversible and covalent interactions receive much attention in the fields of chemical biology and medicinal chemistry. Here, we report two electron-deficient olefins activated by amide and ester,… read more here.
Keywords: targeting thiols; thiols reversible; reversible covalent; new electrophiles ... See more keywords