Targeting tumors with cyclic RGD-conjugated lipid nanoparticles loaded with an IR780 NIR dye: In vitro and in vivo evaluation.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.03.007
Abstract: Like several 50nm-large nanocarriers, lipid nanoparticles (LNPs) can passively accumulate in tumors through the Enhanced Permeability and Retention (EPR) effect. In this study, we developed PEGylated LNPs loaded with IR780 iodide as a contrast agent… read more here.
Keywords: cyclic rgd; crgd lnps; loaded ir780; lipid nanoparticles ... See more keywords
Targeting tumors and financial toxicity in AYAs: Exceptional response to dual immunotherapy in an uninsured young adult with soft tissue sarcoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e23530
Abstract: e23530Background: Rising healthcare costs and patient financial toxicities are a pressing issue for the 70,000 AYAs diagnosed annually in the US. To address both of these issues, Bon Secours St. Fr... read more here.
Keywords: financial toxicity; toxicity ayas; ayas exceptional; tumors financial ... See more keywords
pH-Sensitive Targeting of Tumors with Chemotherapy-Laden Nanoparticles: Progress and Challenges
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112427
Abstract: Accumulating chemotherapeutic drugs such as doxorubicin within a tumor while limiting the drug dose to normal tissues is a central goal of drug delivery with nanoparticles. Liposomal products such as Doxil® represent one of the… read more here.
Keywords: targeting tumors; sensitive targeting; chemotherapeutic agents; tumors chemotherapy ... See more keywords