Targeting tumour-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Gut"
DOI: 10.1136/gutjnl-2022-327230
Abstract: Objective Intrahepatic cholangiocarcinoma (ICC) exhibits very low response rate to immune checkpoint inhibitors (ICIs) and the underlying mechanism is largely unknown. We investigate the tumour immune microenvironment (TIME) of ICCs and the underlying regulatory mechanisms… read more here.
Keywords: time; anti efficacy; mouse; efficacy ... See more keywords
Targeting tumour metastasis: the emerging role of nanotechnology.
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DOI: 10.2174/0929867326666181220095343
Abstract: Metastatic process has still not been completely elucidated, probably due to insufficient knowledge of the underlying mechanisms. Here, we provide an overview of the current findings that shed light on specific molecular alterations associated with… read more here.
Keywords: targeting tumour; tumour metastasis; emerging role; metastasis ... See more keywords