Targeting Unoccupied Surfaces on Protein-Protein Interfaces.
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DOI: 10.1021/jacs.7b05960
Abstract: The use of peptidomimetic scaffolds to target protein-protein interfaces is a promising strategy for inhibitor design. The strategy relies on mimicry of protein motifs that exhibit a concentration of native hot spot residues. To address… read more here.
Keywords: unoccupied surfaces; protein interfaces; protein protein; targeting unoccupied ... See more keywords