Structural Dynamics-Driven Discovery of Anticancer and Antimetastatic Effects of Diltiazem and Glibenclamide Targeting Urokinase Receptor.
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DOI: 10.1021/acs.jmedchem.2c01663
Abstract: Diltiazem and glibenclamide are commonly used hypotensive and antidiabetic drugs. This study reports the discovery of the potential antitumor and antimetastatic effects of these two drugs using a structural dynamics-driven virtual screening targeting urokinase receptor… read more here.
Keywords: antimetastatic effects; dynamics driven; diltiazem glibenclamide; targeting urokinase ... See more keywords