Articles with "targeting wild" as a keyword



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Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12040548

Abstract: TP53 is a tumor suppressor gene that encodes a sequence-specific DNA-binding transcription factor activated by stressful stimuli; it upregulates target genes involved in growth suppression, cell death, DNA repair, metabolism, among others. TP53 is the… read more here.

Keywords: mutant p53; p53 cancer; p53; targeting wild ... See more keywords