Integration of metabolomics and transcriptomics to reveal metabolic characteristics and key targets associated with cisplatin resistance in non-small cell lung cancer.
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DOI: 10.1021/acs.jproteome.9b00209
Abstract: Continuous exposure to cisplatin can induce drug resistance to limit efficacy, however, the underlying mechanisms correlated to cisplatin resistance are still unclear. Drug-sensitive A549 cells and cisplatin-resistant A549/DDP cells were used to explore the potential… read more here.
Keywords: metabolism; key targets; a549 ddp; targets associated ... See more keywords