Several targets involved in Alzheimer’s disease amyloidogenesis are affected by morin and isoquercitrin
Sign Up to like & getrecommendations! Published in 2018 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2018.1534793
Abstract: Long-term consumption of phytochemicals has been associated with a decreased risk of dementia. The modes of action of two flavonols (morin and isoquercitrin) and two flavanones (hesperidin and neohesperidin) were characterized as single-compound drugs in… read more here.
Keywords: several targets; alzheimer disease; morin isoquercitrin; targets involved ... See more keywords
Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010743
Abstract: The tripartite motif (TRIM) family of E3 ubiquitin ligases is well known for its roles in antiviral restriction and innate immunity regulation, in addition to many other cellular pathways. In particular, TRIM25-mediated ubiquitination affects both… read more here.
Keywords: elucidation trim25; ubiquitination targets; trim25 ubiquitination; targets involved ... See more keywords
Mitochondrial proteomics reveal potential targets involved in mitochondrial abnormalities of desminopathy.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical neuropathology"
DOI: 10.5414/np300969
Abstract: AIMS To investigate the underlying mechanisms of how the defects of desmin cause mitochondrial abnormalities in desminopathy. MATERIAL AND METHODS Primary myoblasts were isolated from muscle biopsy of a desminopathy patient with mitochondrial abnormalities. Two-dimensional… read more here.
Keywords: mitochondrial proteomics; involved mitochondrial; potential targets; targets involved ... See more keywords