Synthesis, In Vitro Evaluation and Molecular Docking of the 5-Acetyl-2-aryl-6-hydroxybenzo[b]furans against Multiple Targets Linked to Type 2 Diabetes
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DOI: 10.3390/biom10030418
Abstract: The 5-acetyl-2-aryl-6-hydroxybenzo[b]furans 2a–h have been evaluated through in vitro enzymatic assay against targets which are linked to type 2 diabetes (T2D), namely, α-glucosidase, protein tyrosine phosphatase 1B (PTP1B) and β-secretase. These compounds have also been… read more here.
Keywords: aryl hydroxybenzo; acetyl aryl; hydroxybenzo furans; targets linked ... See more keywords
Identification of Potential Targets Linked to the Cardiovascular/Alzheimer’s Axis through Bioinformatics Approaches
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DOI: 10.3390/biomedicines10020389
Abstract: The identification of common targets in Alzheimer’s disease (AD) and cardiovascular disease (CVD) in recent years makes the study of the CVD/AD axis a research topic of great interest. Besides aging, other links between CVD… read more here.
Keywords: linked cardiovascular; identification potential; axis; potential targets ... See more keywords