Berberine Directly Targets the NEK7 Protein to Block the NEK7-NLRP3 Interaction and Exert Anti-inflammatory Activity.
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DOI: 10.1021/acs.jmedchem.0c01743
Abstract: Berberine (BBR), a traditional Chinese medicine, has therapeutic effects on a variety of inflammation-related diseases, but its direct proteomic targets remain unknown. Using activity-based protein profiling, we first demonstrated that BBR directly targets the NEK7… read more here.
Keywords: nlrp3 interaction; targets nek7; directly targets; nek7 nlrp3 ... See more keywords