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   Articles with "targets potential" as a keyword



Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.

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recommendations! Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.112311

Abstract: Nonalcoholic Fatty Liver Disease (NAFLD) is the most common chronic liver disease in the world, which is characterized by liver fat accumulation unrelated to excessive drinking. Indeed, it attracts growing attention and becomes a global… read more here.

Keywords: fatty liver; disease; targets potential; potential therapeutic ... See more keywords

Gastroparesis syndromes: emerging drug targets and potential therapeutic opportunities

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recommendations! Published in 2023 at "Expert Opinion on Investigational Drugs"

DOI: 10.1080/13543784.2023.2186222

Abstract: ABSTRACT Introduction Gastroparesis (Gp) and related disorders such as chronic unexplained nausea and vomiting and functional dyspepsia, known as gastropareis syndromes (GpS), have large unmet needs. Mainstays of GpS treatments are diet and drugs. Areas… read more here.

Keywords: drug targets; gastroparesis syndromes; targets potential; syndromes emerging ... See more keywords

MOLECULAR TARGETS AS POTENTIAL PI3Kα INHIBITORS AGAINST AGGRESSIVE METASTATIC DUCTAL AND LOBULAR CARCINOMA

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recommendations! Published in 2024 at "International Journal of Applied Pharmaceutics"

DOI: 10.22159/ijap.2024v16i5.51514

Abstract: Objective: This study aimed to identify active compounds among existing molecules by drug repositioning as potential hits of Phosphoinositide 3-Kinase (PI3Kα) inhibitors. FDA-approved ligands were docked using structure-based in silico screening, and the top ten… read more here.

Keywords: potential pi3k; two molecules; targets potential; molecular targets ... See more keywords

Progress of tanshinone IIA against respiratory diseases: therapeutic targets and potential mechanisms

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recommendations! Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1505672

Abstract: The respiratory system stands as one of the eight pivotal systems within the human body, responsible for a range of essential functions. Primarily, it facilitates the absorption of oxygen from the external environment and the… read more here.

Keywords: respiratory diseases; targets potential; tan iia; tanshinone iia ... See more keywords