Quantitative Chemical Proteomic Profiling of the in Vivo Targets of Reactive Drug Metabolites.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.7b00346
Abstract: Idiosyncratic liver toxicity represents an important problem in drug research and pharmacotherapy. Reactive drug metabolites that modify proteins are thought to be a principal factor in drug-induced liver injury. Here, we describe a quantitative chemical… read more here.
Keywords: targets reactive; drug metabolites; drug; reactive drug ... See more keywords