Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-5326-1
Abstract: BackgroundBoth human and mouse fibroblasts can be reprogrammed to pluripotency with Oct4, Sox2, Klf4, and c-Myc (OSKM) transcription factors. While both systems generate pluripotency, human reprogramming takes considerably longer than mouse.ResultsTo assess additional similarities and… read more here.
Keywords: targets reveals; comparison reprogramming; factor targets; reveals species ... See more keywords