Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins
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DOI: 10.1021/acschembio.0c00325
Abstract: Coibamide A (CbA) is a marine natural product with potent antiproliferative activity against human cancer cells and a unique selectivity profile. Despite promising antitumor activity, the mechanism of cytotoxicity and specific cellular target of CbA… read more here.
Keywords: targets sec61; cba; secretory membrane;