Proteome-wide Mendelian randomization and colocalization analysis identify therapeutic targets for stroke
Sign Up to like & getrecommendations! Published in 2025 at "BMC Neurology"
DOI: 10.1186/s12883-025-04239-9
Abstract: Stroke is a leading cause of death and disability worldwide, yet its treatment still faces significant challenges. Mendelian randomization (MR) has been widely used to discover new biomarkers and therapeutic targets. This study aimed to… read more here.
Keywords: therapeutic targets; targets stroke; stroke; drug ... See more keywords
Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.00070
Abstract: Stroke remains a leading cause of death, disability, and medical care burden worldwide. However, transformation from laboratory findings toward effective pharmacological interventions for clinical stroke has been unsatisfactory. Novel evidence has been gained on the… read more here.
Keywords: targets stroke; trpc channels; channels trpc6; trpc ... See more keywords