Articles with "tariquidar pet" as a keyword



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Measurement of hepatic ABCB1 and ABCG2 transport activity with [11C]tariquidar and PET in humans and mice.

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Published in 2019 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.9b01060

Abstract: P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) in the canalicular membrane of hepatocytes mediate the biliary excretion of drugs and drug metabolites. To measure hepatic ABCB1 and ABCG2 activity, we performed positron emission tomography… read more here.

Keywords: tariquidar pet; activity; tariquidar; 11c tariquidar ... See more keywords