TASOR expression in naive embryonic stem cells safeguards their developmental potential
Sign Up to like & getrecommendations! Published in 2024 at "Cell reports"
DOI: 10.1101/2024.02.25.581951
Abstract: The seamless transition through stages of pluripotency relies on a delicate balance between transcription factor networks and epigenetic silencing mechanisms that ensure proper regulation of the developmental program, critical for normal development. Here, we uncover… read more here.
Keywords: expression naive; naive embryonic; tasor expression; transition ... See more keywords
Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx.
Sign Up to like & getrecommendations! Published in 2021 at "PLoS pathogens"
DOI: 10.1371/journal.ppat.1009609
Abstract: Human Immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2) succeed to evade host immune defenses by using their viral auxiliary proteins to antagonize host restriction factors. HIV-2/SIVsmm Vpx is known for degrading SAMHD1, a… read more here.
Keywords: hiv vpx; degradation; tasor; vpx ... See more keywords