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Published in 2021 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2021.106977
Abstract: Methylone's rewarding effects have been well characterized; however, little is known about its aversive effects and how such effects may be impacted by sex. In this context, the present study investigated the aversive effects of…
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Keywords:
taste;
taste avoidance;
aversive effects;
sex ... See more keywords
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Published in 2019 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2019.172801
Abstract: Speedball (heroin + cocaine) is a prevalent drug combination among intravenous drug users. Although its use is generally discussed to be a function of changes in the rewarding effects of either or both drugs, changes in the…
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Keywords:
combination;
taste avoidance;
heroin cocaine;
heroin ... See more keywords
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Published in 2022 at "Communications Biology"
DOI: 10.1038/s42003-021-02956-8
Abstract: Previously, we reported that DAF-2c, an axonal insulin receptor isoform in Caenorhabditis elegans , acts in the ASER gustatory neuron to regulate taste avoidance learning, a process in which worms learn to avoid salt concentrations…
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Keywords:
daf signaling;
taste avoidance;
starvation;
avoidance ... See more keywords
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2204238119
Abstract: Significance Organisms face many new threats in the Anthropocene Epoch. We examine exposure to elevated concentrations of heavy metals as a paradigmatic threat, using fruit flies as a model organism. Release of metals into the…
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Keywords:
metal ions;
taste avoidance;
avoidance;
threat ... See more keywords
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3
Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyac025
Abstract: The ubiquitin-proteasome system is associated with various phenomena including learning and memory. In this paper, we report that E3 ubiquitin ligase homologs and the proteasome function are involved in taste avoidance learning, a type of…
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Keywords:
ligase genes;
ubiquitin ligase;
avoidance learning;
hect type ... See more keywords
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Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13040585
Abstract: Background: Prior work has reported that a drug’s aversive effects (as indexed by taste avoidance conditioning) are attenuated when the pre-exposure and conditioning drugs are the same or different. The latter, otherwise known as cross-drug…
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Keywords:
aversive effects;
taste avoidance;
methylone pre;
avoidance ... See more keywords